Biomaterials and Tissues

Tissue characterization

Many products developed by the pharmaceutical industry have a direct effect on the patient’s tissue mechanical properties (e.g., medications for blood pressure, osteoporosis, osteoarthritis, etc). Therefore, it is often desirable to characterize tissue properties before and after the administration of those drugs to assess efficacy. Bose® test instruments offer many different loading and measurement capabilities utilizing the frictionless Bose linear motor technology. These in vitro tests can be used to minimize the scope of animal testing by mimicking the in vivo environment in the lab.

Biomaterials testing

Pharmaceuticals oftentimes require the use of biomaterials either as carriers or delivery systems.  The mechanical properties of these biomaterials are most likely critical for their success.  For example, biodegradable biomaterials (either naturally occurring such as collagen and cellulose or synthetic such as polyesters and polyurethanes) may be used as carriers and the drug release rate greatly depends on the degradation rate of the material and their mechanical integrity.  Bose systems are suitable for applying physiologically-relevant loading while measuring biomaterial properties real-time as the material degrades in heated saline baths.

Key Testing Performance Benefits